Search results for "Genital tract"

showing 2 items of 2 documents

Seminal plasma-induced suppression of the respiratory burst of polymorphonuclear leukocytes and monocytes.

1984

Summary: Based on recent findings indicating suppression of lymphocytic functions by seminal plasma (SP) we tested the effects of SP from men with normo- and oligozoospermia (n = 7, each) on the generation of luminol-enhanced chemiluminescence (CL) of polymorphonuclear leukocytes (PMN) and monocytes (Mo) stimulated in vitro with zymosan. We found a complete suppression of CL of PMN and Mo by undiluted SP's, 1,000-fold dilutions still induced ≥ 20 percent inhibition. There was no difference between normo- and oligozoospermic men in inhibition of CL both with PMN and Mo. Protein concentrations of SP's were closely the same; all SP were free of the complement components C4 and C3c. After dialy…

Malemedicine.medical_specialtyNeutrophilsUrologyPercent InhibitionMonocytesComplement componentschemistry.chemical_compoundEndocrinologyOxygen ConsumptionSemenInternal medicinemedicineHumansImmunosuppression TherapyMonocyteZymosanProteinsGeneral MedicineComplement System ProteinsOligospermiaMolecular biologyRespiratory burstEndocrinologymedicine.anatomical_structurechemistryGenital tractLuminescent MeasurementsAndrologia
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Sarcoma Botryoides: Optimal Therapeutic Management and Prognosis of an Unfavorable Malignant Neoplasm of Female Children

2023

Embryonal rhabdomyosarcoma (ERMS) is a rare malignancy and occurs primarily in the first two decades of life. Botryoid rhabdomyosarcoma is an aggressive subtype of ERMS that often manifests in the genital tract of female infants and children. Due to its rarity, the optimal treatment approach has been a matter of debate. We conducted a search in the PubMed database and supplemented it with a manual search to retrieve additional papers eligible for inclusion. We retrieved 13 case reports and case series, from which we summarized that the current trend is to approach each patient with a personalized treatment plan. This consists of a combination of local debulking surgery and adjuvant or neoad…

Clinical BiochemistryEmbryonal rhabdomyosarcoma Fertility-sparing surgery Genital tract Local debulking Neoadjuvant chemotherapy Prognosis Radiation Sarcoma botryoides TreatmentSettore MED/40 - Ginecologia E OstetriciaDiagnostics
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